Wissenschaftliche Untersuchungen zu Zell-Vitalstoffen in der Krebsbekämpfung
Klinische Studien zu Zell-Vitalstoffen
In englischer Sprache.
Dietary antioxidant intake and the risk of cardia cancer and noncardia cancer of the intestinal and diffuse types: a population-based case-control study in Sweden
Int J Cancer 2000 Jul 1;87(1):133-40
Ekstrom AM; Serafini M; Nyren O; Hansson LE; Ye W; Wolk A
Dietary carotenoids and vitamins A, C, and E and risk of breast cancer.
J Natl Cancer Inst 1999 Mar 17;91(6):547-56
Zhang S; Hunter DJ; Forman MR; Rosner BA; Speizer FE; Colditz GA; Manson JE; Hankinson SE; Willett WC
A new concept of tumor promotion by tumor necrosis factor-alpha, and cancer preventive agents (-)-epigallocatechin gallate and green tea--a review.
Cancer Detect Prev 2000;24(1):91-9
Fujiki H; Suganuma M; Okabe S; Sueoka E; Suga K; Imai K; Nakachi K
Two stages of cancer prevention with green tea.
J Cancer Res Clin Oncol 1999 Nov;125(11):589-97
Fujiki H
Cancer inhibition by green tea.
Mutat Res 1998 Jun 18;402(1-2):307-10
Fujiki H; Suganuma M; Okabe S; Sueoka N; Komori A; Sueoka E; Kozu T; Tada Y; Suga K; Imai K; Nakachi K
Severe hypovitaminosis C in lung-cancer patients: the utilization of vitamin C in surgical repair and lymphocyte-related host resistance.
Br J Cancer 1982 Sep;46(3):354-67
Anthony HM; Schorah CJ
Ascorbic acid in the plasma and blood cells of women with breast cancer. The effect of the consumption of food with an elevated content of this vitamin
Nutr Hosp 1995 Nov-Dec;10(6):368-72
Nunez Martin C ; Ortiz de Apodaca y Ruiz A
Endogenous urinary 3-hydroxyproline has 96% specificity and 44% sensitivity for cancer screening.
J Lab Clin Med 1992 Dec;120(6):908-20
Okazaki I ; Matsuyama S ; Suzuki F; Maruyama K; Maruta A; Kubochi K; Yoshino K; Kobayashi Y; Abe O; Tsuchiya M
Forschungsdaten zu Zell-Vitalstoffen
In englischer Sprache.
Anticlastogenic, antigenotoxic and apoptotic activity of epigallocatechin gallate: a green tea polyphenol.
Roy M, Chakrabarty S, Sinha D, Bhattacharya RK, Siddiqi M.
Decreased incidence of prostate cancer with selenium supplementation: results of a double-blind cancer prevention trial.
Br J Urol 1998 May;81(5):730-4
Clark LC; Dalkin B; Krongrad A; Combs GF; Turnbull BW; Slate EH; Witherington R; Herlong JH; Janosko E; Carpenter D; Borosso C; Falk S; Rounder J
Induction of p57 is required for cell survival when exposed to green tea polyphenols.
Anticancer Res 2002 Nov-Dec;22(6C):4115-20
Hsu S; Yu FS; Lewis J; Singh B; Borke J; Osaki T; Athar M; Schuster G
Selenium effects on prostate cell growth.
Cancer Epidemiol Biomarkers Prev 2000 Nov;9(11):1171-82
Menter DG; Sabichi AL; Lippman SM
P53 gene of chang-liver cells (Atcc-Ccl13) exposed to aflatoxin B1 (Afb): the effect of lysine on mutation at codon 249 of exon 7.
Afr J Med Med Sci. 1999 Mar-Jun;28(1-2):71-5.
Uwaifo O.
Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis.
Dermatologica. 1987;175(4):183-90
Griffith RS, Walsh DE, Myrmel KH, Thompson RW, Behforooz A.
Amino acid deficiency up-regulates specific mRNAs in murine embryonic cells.
J Nutr. 2002 Aug;132(8):2137-42
Fontanier-Razzaq N, Harries DN, Hay SM, Rees WD.
Identification and characterization of amino acid starvation-induced CD24 gene in MCF-7 human breast cancer cells.
Int J Oncol. 2000 May;16(5):1049-54
Liu W, Vadgama JV.
Retinoids and differentiation treatment: a strategy for treatment in cancer.
Anticancer Res 1994 Nov-Dec;14(6A):2339-46
Cornic M; Agadir A; Degos L; Chomienne C
Cell signaling and regulators of cell cycle as molecular targets for prostate cancer prevention by dietary agents.
Biochem Pharmacol 2000 Oct 15;60(8):1051-9
Agarwal R
Association of suppression of extracellular signal-regulated kinase phosphorylation by epigallocatechin gallate with the reduction of matrix metalloproteinase activities in human fibrosarcoma HT1080 cells.
J Agric Food Chem 2003 Mar 26;51(7):1858-63
Maeda-Yamamoto M; Suzuki N; Sawai Y; Miyase T; Sano M; Hashimoto-Ohta A; Isemura M
Inhibitory effects of tea catechins, black tea extract and oolong tea extract on hepatocarcinogenesis in rat.
Jpn J Cancer Res 1996 Oct;87(10):1034-8
Matsumoto N; Kohri T; Okushio K; Hara Y
Tea polyphenols down-regulate the expression of the androgen receptor in LNCaP prostate cancer cells.
Oncogene 2000 Apr 6;19(15):1924-32
Ren F; Zhang S; Mitchell SH; Butler R; Young CY
Induction of apoptosis and cell cycle arrest in cancer cells by in vivo metabolites of teas.
Nutr Cancer 2000;38(2):265-73
Zhang G; Miura Y; Yagasaki K
Tea catechins and related polyphenols as anti-cancer agents
Biofactors 2000;13(1-4):81-5
Isemura M; Saeki K; Kimura T; Hayakawa S; Minami T; Sazuka M
Green tea catechins and vitamin E inhibit angiogenesis of human microvascular endothelial cells through suppression of IL-8 production
Nutr Cancer 2001;41(1-2):119-25
Tang FY; Meydani M
Green tea polyphenols induce apoptosis in vitro in peripheral blood T lymphocytes of adult T-cell leukemia patients
Jpn J Cancer Res 2000 Jan;91(1):34-40
Li HC; Yashiki S; Sonoda J; Lou H; Ghosh SK; Byrnes JJ; Lema C; Fujiyoshi T; Karasuyama M; Sonoda S
Tea catechin synergies in inhibition of cancer cell proliferation and of a cancer specific cell surface oxidase (ECTO-NOX)
Pharmacol Toxicol 2003 May;92(5):234-41
Morre DJ; Morre DM; Sun H; Cooper R; Chang J; Janle EM
Involvement of protein tyrosine phosphorylation in the effect of green tea polyphenols on Ehrlich ascites tumor cells in vitro.
Chem Biol Interact 1998 Apr 3;110(3):159-72
Kennedy DO; Nishimura S; Hasuma T; Yano Y; Otani S; Matsui-Yuasa I
Potent inhibitory action of red wine polyphenols on human breast cancer cells.
J Cell Biochem 2000 Jun 6;78(3):429-41
Damianaki A; Bakogeorgou E; Kampa M; Notas G; Hatzoglou A; Panagiotou S; Gemetzi C; Kouroumalis E; Martin PM; Castanas E
Green tea: cancer preventive beverage and/or drug.
Cancer Lett 2002 Dec 15;188(1-2):9-13
Fujiki H; Suganuma M; Imai K; Nakachi K
Green tea polyphenol epigallocatechin-3 gallate inhibits Her-2/neu signaling, proliferation, and transformed phenotype of breast cancer cells.
Cancer Res 2002 Feb 1;62(3):652-5
Pianetti S; Guo S; Kavanagh KT; Sonenshein GE
Green tea (Camellia sinensis) extract and its possible role in the prevention of cancer.
Altern Med Rev 1999 Oct;4(5):360-70
Brown MD
Cell cycle dysregulation by green tea polyphenol epigallocatechin-3-gallate.
Biochem Biophys Res Commun 2000 Aug 28;275(2):328-34
Ahmad N; Cheng P; Mukhtar H
Green tea polyphenol targets the mitochondria in tumor cells inducing caspase 3-dependent apoptosis.
Anticancer Res 2003 Mar-Apr;23(2B):1533-9
Hsu S; Lewis J; Singh B; Schoenlein P; Osaki T; Athar M; Porter AG; Schuster G
Involvement of caspase-3 in epigallocatechin-3-gallate-mediated apoptosis of human chondrosarcoma cells.
Biochem Biophys Res Commun 2000 Apr 21;270(3):793-7
Islam S; Islam N; Kermode T; Johnstone B; Mukhtar H; Moskowitz RW; Goldberg VM; Malemud CJ; Haqqi TM
Epigallocatechin gallate protects U937 cells against nitric oxide-induced cell cycle arrest and apoptosis.
J Cell Biochem 2001;81(4):647-58
Kelly MR; Geigerman CM; Loo G
Green tea polyphenol epigallocatechin-3 gallate induces apoptosis of proliferating vascular smooth muscle cells via activation of p53.
FASEB J 2003 Apr;17(6):702-4
Hofmann CS; Sonenshein GE
Effect of vitamin C on prostate cancer cells in vitro: effect on cell number, viability, and DNA synthesis.
Prostate 1997 Aug 1;32(3):188-95
Maramag C; Menon M; Balaji KC; Reddy PG; Laxmanan S
Effect of vitamin C on androgen independent prostate cancer cells (PC3 and Mat-Ly-Lu) in vitro: involvement of reactive oxygen species-effect on cell number, viability and DNA synthesis.
Cancer Biochem Biophys 1998 Jun;16(1-2):17-30
Menon M; Maramag C; Malhotra RK; Seethalakshmi L
Combined vitamins B12b and C induce the glutathione depletion and the death of epidermoid human larynx carcinoma cells HEp-2.
Biosci Rep 2000 Oct;20(5):411-7
Akatov VS; Evtodienko YV; Leshchenko VV; Teplova VV; Potselueva MM; Kruglov AG; Lezhnev EI; Yakubovskaya RI
Antimetastatic and anti-invasive ability of phospho-ascorbyl palmitate through intracellular ascorbate enrichment and the resultant antioxidant action
Oncol Res 1999;11(10):479-87
Liu JW; Nagao N; Kageyama K; Miwa N
Inhibitory effect of dietary arginine on growth of Ehrlich ascites tumor cells in mice.
J Nutr 1979 Mar;109(3):489-94
Milner JA; Stepanovich LV
Dietary copper and dimethylhydrazine affect protein kinase C isozyme protein and mRNA expression and the formation of aberrant crypts in colon of rats.
Biofactors 2001;15(1):11-26
Davis CD; Johnson WT
(-)-Epigallocatechin-3-gallate in Camellia sinensis leaves from Himalayan region of Sikkim: inhibitory effects against biochemical events and tumor initiation in Sencar mouse skin.
Nutr Cancer 1992;18(1):73-83
Katiyar SK; Agarwal R; Wang ZY; Bhatia AK; Mukhtar H
Detrimental effect of cancer preventive phytochemicals silymarin, genistein and epigallocatechin 3-gallate on epigenetic events in human prostate carcinoma DU145 cells.
Prostate 2001 Feb 1;46(2):98-107
Bhatia N; Agarwal R
Green tea and its catechins inhibit breast cancer xenografts.
Nutr Cancer 2001;40(2):149-56
Sartippour MR; Heber D; Ma J; Lu Q; Go VL; Nguyen M
(-)-Epigallocatechin gallate can prevent cisplatin-induced lung tumorigenesis in A/J mice.
Carcinogenesis 2000 May;21(5):915-9
Mimoto J; Kiura K; Matsuo K; Yoshino T; Takata I; Ueoka H; Kataoka M; Harada M
(-)-Epigallocatechin (EGC) of green tea induces apoptosis of human breast cancer cells but not of their normal counterparts.
Breast Cancer Res Treat 2002 Dec;76(3):195-201
Vergote D; Cren-Olive C; Chopin V; Toillon RA; Rolando C; Hondermarck H; Le Bourhis X
Gene expression profile in human prostate LNCaP cancer cells by (--) epigallocatechin-3-gallate.
Cancer Lett 2002 Aug 8;182(1):43-51
Wang SI; Mukhtar H
Green tea and prostate cancer.
Urol Clin North Am 2002 Feb;29(1):49-57, viii
Gupta S; Mukhtar H
Epigallocathechin-3 gallate selectively inhibits the PDGF-BB-induced intracellular signaling transduction pathway in vascular smooth muscle cells and inhibits transformation of sis-transfected NIH 3T3 fibroblasts and human glioblastoma cells (A172).
Mol Biol Cell 1999 Apr;10(4):1093-104
Ahn HY; Hadizadeh KR; Seul C; Yun YP; Vetter H; Sachinidis A
Inhibitory effects of green tea infusion on in vitro invasion and in vivo metastasis of mouse lung carcinoma cells.
Cancer Lett 1995 Nov 27;98(1):27-31
Sazuka M; Murakami S; Isemura M; Satoh K; Nukiwa T
Inhibition of tumour invasion and angiogenesis by epigallocatechin gallate (EGCG), a major component of green tea.
Int J Exp Pathol 2001 Dec;82(6):309-16
Jung YD; Ellis LM
Novel approaches to chemoprevention of skin cancer.
J Dermatol. 2000 Nov;27(11):691-5.
Bickers DR, Athar M.
A major constituent of green tea, EGCG, inhibits the growth of a human cervical cancer cell line, CaSki cells, through apoptosis, G(1) arrest, and regulation of gene expression.
DNA Cell Biol 2003 Mar;22(3):217-24
Ahn WS; Huh SW; Bae SM; Lee IP; Lee JM; Namkoong SE; Kim CK; Sin JI A
Inhibition of bladder tumor growth by the green tea derivative epigallocatechin-3-gallate.
J Urol 2003 Sep;170(3):773-6
Kemberling JK; Hampton JA; Keck RW; Gomez MA; Selman SH
Anticarcinogenic activity of green tea polyphenols.
Jpn J Clin Oncol 1993 Jun;23(3):186-90
Komori A; Yatsunami J; Okabe S; Abe S; Hara K; Suganuma M; Kim SJ; Fujiki H
Inhibition of skin tumor promoter-caused induction of epidermal ornithine decarboxylase in SENCAR mice by polyphenolic fraction isolated from green tea and its individual epicatechin derivatives.
Cancer Res 1992 Jul 1;52(13):3582-8
Agarwal R; Katiyar SK; Zaidi SI; Mukhtar H
Molecular targets for green tea in prostate cancer prevention.
J Nutr 2003 Jul;133(7 Suppl):2417S-2424S
Adhami VM; Ahmad N; Mukhtar H
Suppression of human pancreatic carcinoma cell growth and invasion by epigallocatechin-3-gallate.
Pancreas 2002 Jul;25(1):45-8
Takada M; Nakamura Y; Koizumi T; Toyama H; Kamigaki T; Suzuki Y; Takeyama Y; Kuroda Y
Biochemical changes in the connective tissue components of malignant tumors and lungs in mice during metastatic spreading and chemotherapy
Vopr Med Khim 1989 Sep-Oct;35(5):30-4
Chubinskaia SG; Sevast'ianova NA; Veksler IG; Slutskii LI
Differential effects and transport kinetics of ascorbate derivatives in leukemic cell lines.
Anticancer Res 1998 Jul-Aug;18(4A):2487-93
Koh WS; Lee SJ; Lee H; Park C; Park MH; Kim WS; Yoon SS; Park K; Hong SI; Chung MH; Park CH
Tea polyphenols: prevention of cancer and optimizing health
Am J Clin Nutr 2000 Jun;71(6 Suppl):1698S-702S; discussion 1703S-4S
Mukhtar H; Ahmad N
Activation mechanisms of matrix metalloproteinases.
Biol Chem 1997 Mar-Apr;378(3-4):151-60
Nagase H
Inhibitory effect of six green tea catechins and caffeine on the growth of four selected human tumor cell lines.
Anticancer Drugs 1996 Jun;7(4):461-8
Valcic S ; Timmermann BN; Alberts DS; Wachter GA; Krutzsch M; Wymer J; Guillen JM
Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols.
Carcinogenesis 1998 Apr;19(4):611-6
Yang GY; Liao J; Kim K; Yurkow EJ; Yang CS
Suppression of extracellular signals and cell proliferation through EGF receptor binding by (-)-epigallocatechin gallate in human A431 epidermoid carcinoma cells.
J Cell Biochem 1997 Oct 1;67(1):55-65
Liang YC; Lin-shiau SY; Chen CF; Lin JK
Matrix metalloproteinase inhibition by green tea catechins.
Biochim Biophys Acta 2000 Mar 16;1478(1):51-60
Demeule M; Brossard M; Page M; Gingras D; Beliveau R
Anti-metastatic effect of an autooxidation-resistant and lipophilic ascorbic acid derivative through inhibition of tumor invasion
Anticancer Res 2000 Jan-Feb;20(1A):113-8
Liu JW; Nagao N; Kageyama K; Miwa N
Growth suppression of malignant leukemia cell line in vitro by ascorbic acid (vitamin C) and its derivatives.
Cancer Lett 1998 Jan 9;122(1-2):93-9
Roomi MW; House D; Eckert-Maksic M; Maksic ZB; Tsao CS
Ascorbic acid (vitamin C) improves the antineoplastic activity of doxorubicin, cisplatin, and paclitaxel in human breast carcinoma cells in vitro.
Cancer Lett 1996 Jun 5;103(2):183-9
Kurbacher CM; Wagner U; Kolster B; Andreotti PE; Krebs D; Bruckner HW
Selenium-induced inhibition of angiogenesis in mammary cancer at chemopreventive levels of intake.
Mol Carcinog 1999 Dec;26(4):213-25
Jiang C; Jiang W; Ip C; Ganther H; Lu J
Inhibition of aminopeptidase N (AP-N) and urokinase-type plasminogen activator (uPA) by zinc suppresses the invasion activity in human urological cancer cells.
Biol Pharm Bull 2001 Mar;24(3):226-30
Ishii K; Usui S; Sugimura Y; Yamamoto H; Yoshikawa K; Hirano K
Novel role of zinc in the regulation of prostate citrate metabolism and its implications in prostate cancer.
Prostate 1998 Jun 1;35(4):285-96
Costello LC; Franklin RB
Esophageal cancer prevention in zinc-deficient rats: rapid induction of apoptosis by replenishing zinc.
J Natl Cancer Inst 2001 Oct 17;93(20):1525-33
Fong LY; Nguyen VT; Farber JL
Induction of apoptosis and necrosis by zinc in human thyroid cancer cell lines.
J Endocrinol 2001 May;169(2):417-24
Iitaka M; Kakinuma S; Fujimaki S; Oosuga I; Fujita T; Yamanaka K; Wada S; Katayama S
Effect of zinc on immune functions and host resistance against infection and tumor challenge.
Immunopharmacol Immunotoxicol 1992;14(4):813-40
Singh KP; Zaidi SI; Raisuddin S; Saxena AK; Murthy RC; Ray PK
Zinc inhibits nuclear factor-kappa B activation and sensitizes prostate cancer cells to cytotoxic agents.
Clin Cancer Res 2002 Nov;8(11):3579-83
Uzzo RG; Leavis P; Hatch W; Gabai VL; Dulin N; Zvartau N; Kolenko VM
Selenium inhibition of N-methyl-N-nitrosourea-induced mammary carcinogenesis in the rat.
J Natl Cancer Inst 1980 Dec;65(6):1299-301
Thompson HJ; Becci PJ
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